Department of Medicine, University of Western Ontario, London, Ontario.
Can Respir J. 2012 Jan-Feb;19(1):50-2. doi: 10.1155/2012/129403.
Desquamative interstitial pneumonia (DIP) is a rare form of interstitial lung disease (ILD) commonly found among healthy smokers. ILD is a rare manifestation of systemic lupus erythematosus (SLE), and typically associated with a histopathological pattern of nonspecific interstitial pneumonia (NSIP). The present article describes an unusual case of DIP in a nonsmoking patient with SLE presenting as NSIP. DIP can occur in the context of SLE in patients with a negative smoking history, and clinicians should consider lung biopsy to correctly classify ILD with unusual presentation on computed tomography scan.
脱屑性间质性肺炎(DIP)是一种罕见的间质性肺疾病(ILD),常见于健康吸烟者。ILD 是系统性红斑狼疮(SLE)的一种罕见表现,通常与非特异性间质性肺炎(NSIP)的组织病理学模式相关。本文描述了一例 SLE 患者出现 NSIP 样表现的非吸烟患者中罕见的 DIP 病例。在无吸烟史的 SLE 患者中可能会发生 DIP,因此,当 CT 扫描显示ILD 表现不典型时,临床医生应考虑进行肺活检以正确分类ILD。