从长春花根部提取的三种新的单体吲哚生物碱。

Three new monomeric indole alkaloids from the roots of Catharanthus roseus.

作者信息

Wang Chun-Hua, Wang Guo-Cai, Wang Ying, Zhang Xiao-Qi, Huang Xiao-Jun, Ye Wen-Cai

机构信息

Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, China.

出版信息

J Asian Nat Prod Res. 2012;14(3):249-55. doi: 10.1080/10286020.2011.649728.

DOI:10.1080/10286020.2011.649728

PMID:22332772

Abstract

Two new alkaloid glycosides (1 and 2) and a new monomeric indole alkaloid (3), together with 13 known ones (4-16), were isolated from the roots of Catharanthus roseus. The structures of new compounds were elucidated on the basis of the spectroscopic methods. The absolute configuration of compound 3 was established by the modified Mosher's method.

摘要

从长春花的根部分离出两种新的生物碱苷（1和2）、一种新的单体吲哚生物碱（3），以及13种已知化合物（4 - 16）。通过光谱方法阐明了新化合物的结构。采用改良的莫舍尔法确定了化合物3的绝对构型。