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穗花杉双黄酮苷类成分研究(来自于穗花杉地上部分)

Indole alkaloid glycosides from the aerial parts of Strobilanthes cusia.

机构信息

Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, People's Republic of China.

出版信息

J Nat Prod. 2014 Dec 26;77(12):2590-4. doi: 10.1021/np5003274. Epub 2014 Nov 26.

Abstract

Three indole alkaloid glycosides, strobilanthosides A-C (1-3), two known indole alkaloid glucosides (4 and 5), and five phenylethanoid glycosides (8-10) were isolated from the aerial parts of Strobilanthes cusia. The structures of the new compounds were elucidated by spectrometric analysis, and the absolute configurations of 1 and 2 were established by ECD spectrocsopy. N'-β-d-Glucopyranosylindirubin (5) showed weak antibacterial activity (MIC 62.5-125 μM) against Staphylococcus aureus.

摘要

从山菅兰的地上部分分离得到三种吲哚生物碱糖苷,即 stroblanthosides A-C(1-3),两种已知的吲哚生物碱葡萄糖苷(4 和 5)和五种苯乙醇苷(8-10)。通过光谱分析阐明了新化合物的结构,并通过 ECD 光谱法确定了 1 和 2 的绝对构型。N'-β-d-葡萄糖吡喃基 indirubin(5)对金黄色葡萄球菌表现出较弱的抗菌活性(MIC 62.5-125 μM)。

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