Shek Samantha Y, Chan Nicola P Y, Chan Henry H
Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Lasers Surg Med. 2012 Feb;44(2):125-30. doi: 10.1002/lsm.21145.
The objective of the study is to determine the clinical efficacy and patient satisfaction of a novel cryolipolysis device (Zeltiq®) for body contouring in Chinese after a single treatment and after 2 treatments at a commercial setting.
Two groups of patients were recruited for this procedure at their own cost. Group A, 21 subjects, received a single treatment and group B, 12 subjects, received 2 treatments, average 3 months apart using the Zeltiq Breeze System®. The thickness of fat at the treatment site was measured by a caliper and the data were collected at baseline and 2 months post-treatment. Standardized clinical photos were also taken at baseline and follow-up visits. Subjective assessment was carried out in the form of a questionnaire. Any adverse effects were documented. Statistical analyses were performed on the data to compare the efficacy after a single treatment and after 2 treatments.
The first group of subjects, received a single treatment, showed that there was a significant improvement (P < 0.0001). The second group of subjects showed that the improvement was significant after 1 and 2 treatments when compared to the baseline. The extent of improvement after the second treatment however, was not as dramatic as the first treatment.
Non-invasive cryolipolysis is effective for body contouring in Chinese. It is shown to have a further improvement with subsequent treatment sessions but of a lesser extent. The second treatment was statistically significant for abdomen, though not for love handles.
本研究的目的是确定一种新型冷冻溶脂设备（Zeltiq®）在商业环境中对中国患者进行单次治疗和两次治疗后身体塑形的临床疗效和患者满意度。
两组患者自费参与本治疗。A组21名受试者接受单次治疗，B组12名受试者接受两次治疗，使用Zeltiq Breeze System®，两次治疗平均间隔3个月。用卡尺测量治疗部位的脂肪厚度，并在基线和治疗后2个月收集数据。在基线和随访时还拍摄了标准化临床照片。以问卷调查的形式进行主观评估。记录任何不良反应。对数据进行统计分析，以比较单次治疗和两次治疗后的疗效。
接受单次治疗的第一组受试者显示有显著改善（P < 0.0001）。第二组受试者显示，与基线相比，在第1次和第2次治疗后改善显著。然而，第二次治疗后的改善程度不如第一次治疗明显。
非侵入性冷冻溶脂对中国患者的身体塑形有效。后续治疗可进一步改善，但改善程度较小。第二次治疗对腹部有统计学意义，对侧腰则无。
