Bychkov V G, Iaroslavskiĭ V E, Ginovker A G, Molokova O A, Zuevskiĭ V P
Med Parazitol (Mosk). 1990 Jul-Aug(4):36-8.
The investigations conducted on Syrian hamsters have revealed that multiple enteral infusions of cold inactivated (t = -10 degrees C) O. felineus metacercariae resulted in the formation of immunocompetent cell and fibroblast infiltrations around the branches of the portal vein. The infestation of animals by viable pathogens led to reduced accommodation of helminths and suppressed cell infiltration in the liver. It is assumed that the native population of the foci become tolerant to the disease with the penetration of noninvasive Opisthorchis larvae into their body and the development of latent forms of helminthiasis.
对叙利亚仓鼠进行的调查显示，多次肠内输注经冷灭活（t = -10摄氏度）的猫后睾吸虫囊蚴，会导致门静脉分支周围形成免疫活性细胞和成纤维细胞浸润。动物受到活病原体感染会导致蠕虫的容纳量减少，并抑制肝脏中的细胞浸润。据推测，随着非侵袭性后睾吸虫幼虫侵入病灶原生种群体内并发展为潜伏形式的蠕虫病，该种群会对该病产生耐受性。
