The Murdoch Children's Research Institute and The University of Melbourne, Melbourne, Australia.
Early Hum Dev. 2012 Aug;88(8):603-7. doi: 10.1016/j.earlhumdev.2012.01.007. Epub 2012 Feb 14.
Previous research on developmental outcomes of infants with congenital heart disease (CHD) has shown delays in both cognitive and motor skills.
To describe outcomes on the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III) for infants with CHD and to compare those findings to published results for similar samples of infants assessed on the 2nd edition of the Bayley Scales (BSID-II).
Prospective cohort.
Of 50 infants with CHD who participated in this longitudinal study (2006-2008) at the Royal Children's Hospital in Melbourne, Australia, 47 were assessed on the Bayley-III (median age=24.5 months), administered by a psychologist or neonatologist. Although neither assessor was blind to the CHD diagnosis, they were unaware of results of previous developmental assessments conducted in this longitudinal study.
For the Bayley-III cognitive composite score, 17.0% of infants showed mild delays (1-2 SD below the mean), 2.1% had moderate delays (2-3 SD below the mean), and none had severe delays (greater than 3 SD below the mean). Motor composite scores showed mild delays in 10.9% of infants and moderate delays in 2.2%; none had severe motor delays. These findings differ from study results using the BSID-II in similar infants.
The Bayley-III may underestimate developmental delay in 2-year-old children with CHD when compared to results of similar children tested at 12-36 months of age on the BSID-II.
先前对先天性心脏病(CHD)婴儿发育结果的研究表明,他们在认知和运动技能方面都存在延迟。
描述在贝利婴幼儿发展量表第三版(Bayley-III)上患有 CHD 的婴儿的结果,并将这些发现与在贝利婴幼儿发展量表第二版(BSID-II)上评估的类似婴儿的发表结果进行比较。
前瞻性队列研究。
在澳大利亚墨尔本皇家儿童医院进行的这项纵向研究(2006-2008 年)中,共有 50 名患有 CHD 的婴儿参与了该研究,其中 47 名婴儿接受了心理学家或新生儿科医生进行的 Bayley-III 评估(中位数年龄=24.5 个月)。尽管两位评估者都没有对 CHD 诊断视而不见,但他们不知道在这项纵向研究中进行的先前发育评估的结果。
对于 Bayley-III 认知综合评分,17.0%的婴儿存在轻度延迟(低于平均值 1-2 个标准差),2.1%存在中度延迟(低于平均值 2-3 个标准差),没有婴儿存在严重延迟(低于平均值 3 个标准差以上)。运动综合评分显示 10.9%的婴儿存在轻度延迟,2.2%存在中度延迟;没有婴儿存在严重运动延迟。这些发现与在类似婴儿中使用 BSID-II 进行的研究结果不同。
与在 12-36 个月大的类似婴儿中使用 BSID-II 测试的结果相比,Bayley-III 可能低估了患有 CHD 的 2 岁儿童的发育延迟。