Sprong Maaike C A, van Brussel Marco, de Vries Linda S, van der Net Janjaap, Nijman Joppe, Breur Johannes M P J, Slieker Martijn G
Center of Child Development, Exercise and Physical Literacy, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.
Children (Basel). 2022 Apr 16;9(4):570. doi: 10.3390/children9040570.
Infants with critical congenital heart defects (CCHDs) are at increased risk for neurodevelopmental delays. The early identification of motor delays is clinically relevant to prevent or reduce long-term consequences. The current study aims to describe the motor-developmental pathways of infants with a CCHD. Motor development was assessed in 215 infants and toddlers using the Dutch version of the Bayley-III. At 3 months ( = 165), 9 months ( = 188), and 18 months ( = 171) the motor composite scores were 97, 98, and 104, respectively. A motor composite score of ≤-2 SD was only seen in 2.4%, 0%, and 2.3%, respectively, with gross motor deficits being observed more often than fine motor deficits (12% vs. 0% at 18 months). Over 90% of infants who scored average at 9 months still did so at 18 months. The majority of infants with below-average gross motor scores (≤-1) at 9 months still had a below-average or delayed motor score (≤-2 SD) at 18 months. Abnormal gross motor scores (≤-2 SD) increased with age. Infants with single-ventricle physiology performed significantly ( ≤ 0.05) worse on both fine and gross motor skills at 9 and 18 months compared to infants with other CCHDs.
患有严重先天性心脏病（CCHD）的婴儿出现神经发育迟缓的风险增加。运动发育延迟的早期识别对于预防或减少长期后果具有临床意义。本研究旨在描述患有CCHD的婴儿的运动发育途径。使用荷兰版贝利婴幼儿发展量表第三版（Bayley-III）对215名婴幼儿的运动发育进行了评估。在3个月（n = 165）、9个月（n = 188）和18个月（n = 171）时，运动综合得分分别为97、98和104。运动综合得分≤-2标准差的情况分别仅在2.4%、0%和2.3%的婴儿中出现，其中大运动缺陷比精细运动缺陷更常见（18个月时为12%对0%）。9个月时得分平均的婴儿中，超过90%在18个月时仍然如此。9个月时大运动得分低于平均水平（≤-1）的大多数婴儿在18个月时运动得分仍低于平均水平或延迟（≤-2标准差）。异常大运动得分（≤-2标准差）随年龄增加。与患有其他CCHD的婴儿相比，单心室生理的婴儿在9个月和18个月时的精细和大运动技能表现明显更差（P≤0.05）。
