State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, PR China.
Lab Chip. 2012 Apr 7;12(7):1281-8. doi: 10.1039/c2lc20985c. Epub 2012 Feb 15.
In this study, steady liquid-gas phase separation is realized by applying a hydrophobic small microchannel array (SMA) to bridge two large microchannels, one for liquid phase and one for gas phase. In this structure, a capillary pressure difference between that in the SMA and the larger channel results in a steady liquid-gas interface. The generated liquid-gas interface allows for fast gas dissolving speed. By coupling the liquid-gas interface with a one directional fluidic field, a steady dissolved gas concentration gradient (DgCG) is generated. The DgCG distribution is easily designable for linear or exponential modes, providing improved flexibility for gas participated processes on chip. To demonstrate its applicability, a CO(2) DgCG chip is fabricated and applied for screening CaCO(3) crystal growth conditions in the DgCG chip. Crystals with transitional structures are successfully fabricated, which is consistent with the CO(2) DgCG distribution.
在这项研究中，通过在两个大微通道之间应用疏水性微小通道阵列 (SMA) 来实现稳定的液-气相间分离，一个用于液相，一个用于气相。在这种结构中，SMA 和较大通道之间的毛细压差会导致稳定的液-气界面。所产生的液-气界面允许快速溶解气体。通过将液-气界面与单向流场耦合，可以产生稳定的溶解气体浓度梯度 (DgCG)。DgCG 分布可以轻松设计为线性或指数模式，为芯片上的气体参与过程提供了更大的灵活性。为了证明其适用性，制作了 CO(2) DgCG 芯片，并将其应用于在 DgCG 芯片中筛选碳酸钙晶体生长条件。成功制备了具有过渡结构的晶体，这与 CO(2) DgCG 分布一致。
