Science & Technology, Corning Incorporated, Corning, New York 14831-0001, USA.
Lab Chip. 2011 Oct 7;11(19):3249-55. doi: 10.1039/c1lc20157c. Epub 2011 Aug 11.
This article presents a simple, low-cost method of fabrication and the applications of flexible polystyrene microfluidic devices with three-dimensional (3D) interconnected microporous walls based on treatment using a solvent/non-solvent mixture at room temperature. The complete fabrication process from device design concept to working device can be completed in less than an hour in a regular laboratory setting, without the need for expensive equipment. Microfluidic devices were used to demonstrate gas generation and absorption reactions by acidifying water with carbon dioxide (CO(2)) gas. By selectively treating the microporous structures with oxygen plasma, acidification of water by acetic acid (distilled white vinegar) perfusion was also demonstrated with the same device design.
本文提出了一种简单、低成本的制造方法,以及基于室温下使用溶剂/非溶剂混合物处理的具有三维(3D)互连微孔壁的柔性聚苯乙烯微流控器件的应用。从设备设计概念到工作设备的完整制造过程可以在不到一个小时的时间内在常规实验室环境中完成,而无需昂贵的设备。微流控器件用于通过用二氧化碳(CO(2))气体酸化水来演示气体生成和吸收反应。通过选择性地用氧气等离子体处理微孔结构,还可以用相同的器件设计演示通过乙酸(蒸馏白醋)灌注使水酸化。