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加拿大不列颠哥伦比亚省脊髓损伤的流行病学:基于人群的行政数据的20年研究

Epidemiology of Spinal Cord Injury in British Columbia, Canada: 20 Years of Population-Based Administrative Data.

作者信息

Bond Michael, Beresford Aidan, Noonan Vanessa, Rotem-Kohavi Naama, Dvorak Marcel, Kwon Brian, Liu Guiping, Sutherland Jason M

机构信息

Centre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.

Praxis Spinal Cord Institute, Vancouver, Canada.

出版信息

Neurotrauma Rep. 2025 Apr 9;6(1):311-321. doi: 10.1089/neur.2025.0012. eCollection 2025.

Abstract

Traumatic spinal cord injury (TSCI) is a debilitating condition that can have significant effects on physical function and overall quality of life. Mechanisms of injury can vary from major trauma to low-energy falls. There has been a recent increase in the number of elderly patients with TSCI. A retrospective analysis of population-based hospital records linked with health care administrative datasets was conducted to measure age-standardized rates of TSCI over time. The study was conducted to describe the epidemiology and demographic characteristics of patients who experienced TSCI between 2001 and 2021 in the province of British Columbia, Canada. Demographic, clinical characteristics, and rates of TSCI were evaluated over time. Linear regression was used to assess changes over time. The study identified 3622 patients with TSCI. The average age at the time of injury was 51.1 (standard deviation [SD] 21.19) and 75.0% were males. The average annual age-standardized rate in this population was 35.4 per million. The overall rate remained stable throughout the study period. The mean age at injury increased from 41.9 to 57.5 over the study period of 2001-2021 ( < 0.001). The most frequent causes of injury were low-energy falls (49.9%) and motor vehicle injuries (36.6%). The proportion of injuries related to falls increased over the study period ( < 0.001). Motor and sensory complete TSCI were seen in higher rates among younger patients, and cervical spine injuries were most common among all age-groups. The rate of TCSI was consistent during the study period, though the demographic of patients and their injury mechanism changed considerably; elderly low-energy falls were an increasing proportion of cases. Continued vigilance in elderly fall prevention is needed to reduce the incidence of TCSI among the elderly.

摘要

创伤性脊髓损伤(TSCI)是一种使人衰弱的疾病,会对身体功能和整体生活质量产生重大影响。损伤机制从重大创伤到低能量跌倒各不相同。近期,老年TSCI患者的数量有所增加。我们对与医疗保健管理数据集相关联的基于人群的医院记录进行了回顾性分析,以衡量TSCI随时间推移的年龄标准化发病率。本研究旨在描述2001年至2021年期间加拿大不列颠哥伦比亚省经历TSCI的患者的流行病学和人口统计学特征。我们对TSCI的人口统计学、临床特征和发病率随时间进行了评估。采用线性回归来评估随时间的变化。该研究共确定了3622例TSCI患者。受伤时的平均年龄为51.1岁(标准差[SD]为21.19),男性占75.0%。该人群的平均年年龄标准化发病率为每百万人口35.4例。在整个研究期间,总体发病率保持稳定。在2001 - 2021年的研究期间,受伤时的平均年龄从41.9岁增加到了57.5岁(<0.001)。最常见的受伤原因是低能量跌倒(49.9%)和机动车事故(36.6%)。在研究期间,与跌倒相关的损伤比例有所增加(<0.001)。年轻患者中运动和感觉完全性TSCI的发生率较高,而颈椎损伤在所有年龄组中最为常见。尽管患者的人口统计学特征及其损伤机制发生了很大变化,但在研究期间TCSI的发病率保持一致;老年低能量跌倒导致的病例比例在增加。需要持续关注预防老年人跌倒,以降低老年人中TCSI的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2f/12040552/b36aa60baabf/neur.2025.0012_figure1.jpg

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