乙型肝炎血清流行率：献血者能否代表普通人群？
Seroprevalence of hepatitis B: do blood donors represent the general population?
作者信息
Karaosmanoglu Hayat Kumbasar, Aydin Ozlem Altuntas, Sandikci Semra, Yamanlar Emine Rahsan, Nazlican Ozcan
机构信息
Infectious Diseases and Clinical Microbiology, Haseki Training and Research Hospital, Istanbul, Turkey.
出版信息
J Infect Dev Ctries. 2012 Feb 13;6(2):181-3. doi: 10.3855/jidc.2084.
INTRODUCTION
In this study, we aimed to compare the HBV seroprevalances of voluntary blood donors and the healthy persons who required premarital screening.
METHODOLOGY
HBsAg ELISA results were collected retrospectively from the records of 9,949 blood donors and 954 healthy persons who required premarital screening.
RESULTS
HBsAg was detected in 182 of 9,949 (%1.8) voluntary blood donors and 32 of 954 (%3.4) healthy persons who required premarital screening. HBsAg seropositivity was significiantly higher in the healthy persons who required premarital screening than in blood donors (p = 0.0016).
CONCLUSION
Premarital screening is mandatory in our country, and it may provide more accurate epidemiological data to determine HBV seroprevalence than in other selected groups such as blood donors.
引言
在本研究中，我们旨在比较自愿献血者和需要婚前筛查的健康人群的乙肝病毒血清流行率。
方法
回顾性收集了9949名献血者和954名需要婚前筛查的健康人的乙肝表面抗原（HBsAg）酶联免疫吸附测定（ELISA）结果。
结果
在9949名自愿献血者中，有182人（1.8%）检测出HBsAg，在954名需要婚前筛查的健康人中，有32人（3.4%）检测出HBsAg。需要婚前筛查的健康人群中HBsAg血清阳性率显著高于献血者（p = 0.0016）。
结论
在我国，婚前筛查是强制性的，与献血者等其他特定人群相比，它可能为确定乙肝病毒血清流行率提供更准确的流行病学数据。
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