Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah-11952, Saudi Arabia.
Malawi Med J. 2021 Sep;33(3):221-225. doi: 10.4314/mmj.v33i3.10.
Viral hepatitis is a major global health problem affecting millions of people worldwide. The main objective of the present study was to estimate the seroprevalence of hepatitis C and hepatitis B in Saudi adults undertaking premarital screening voluntarily.
This observational retrospective study was conducted at King Khaled General Hospital, Al Majmaah, Saudi Arabia, for a period of 3 years (October 1, 2016 to September 30, 2019). The prevalence of hepatitis B and hepatitis C infections was calculated using Microsoft Excel and the hematological data analysis was performed using SPSS software. A total of 3755 premarital Saudi adults who voluntarily participated in the premarital screening were included in this study. Subjects were screened for hepatitis C virus (HCV) and hepatitis B virus (HBV). The demographic and epidemiological parameters included patient age, sex, nationality, and seropositivity for HBV and/or HCV.
Of the 3755 subjects, eight (0.242%) and 12 (0.364%) subjects were positive for HCV and HBV, respectively. Among the 12 HBV-positive subjects, nine (75%) subjects were men, and three (25%) subjects were women. However, among the eight HCV-positive subjects, five (62.5%) subjects were men, and three (37.5%) subjects were women.
This study concluded that the prevalence of HBV infection was slightly higher than that of HCV infection among the Saudi adult population of Al Mjamaah. In addition, both HBV and HCV were less prevalent in women than in men in the study population.
病毒性肝炎是一个全球性的健康问题，影响着全世界数百万人。本研究的主要目的是估计在沙特自愿接受婚前检查的成年人中丙型肝炎和乙型肝炎的血清流行率。
这项观察性回顾性研究是在沙特阿拉伯 Al Majmaah 的 King Khaled 综合医院进行的，为期 3 年（2016 年 10 月 1 日至 2019 年 9 月 30 日）。使用 Microsoft Excel 计算乙型肝炎和丙型肝炎感染的流行率，使用 SPSS 软件进行血液学数据分析。本研究共纳入 3755 名自愿参加婚前检查的沙特成年人。对丙型肝炎病毒（HCV）和乙型肝炎病毒（HBV）进行筛查。人口统计学和流行病学参数包括患者年龄、性别、国籍以及 HBV 和/或 HCV 的血清阳性率。
在 3755 名受试者中，有 8 名（0.242%）和 12 名（0.364%）受试者 HCV 和 HBV 阳性。在 12 名 HBV 阳性受试者中，9 名（75%）为男性，3 名（25%）为女性。然而，在 8 名 HCV 阳性受试者中，5 名（62.5%）为男性，3 名（37.5%）为女性。
本研究表明，在 Al Mjamaah 的沙特成年人中，HBV 感染的流行率略高于 HCV 感染。此外，在研究人群中，HBV 和 HCV 在女性中的流行率均低于男性。
