Department of Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
Am J Clin Pathol. 2012 Mar;137(3):346-55. doi: 10.1309/AJCPS26UKHNYCEAV.
Personalized medicine and health care reform offer the opportunity for pathologists to have a more central and visible role in patient care. Pathologists face new and more complicated requests for clinical and research testing on tissue specimens, including testing for somatic and inherited mutations. Pathologists must comprehend the applications and requirements for molecular testing and their legal and ethical responsibilities in handling tissue requests for clinical and research purposes to best serve the needs of patients and clinicians and to comply with federal and state laws. This article reviews these rapidly evolving and complex areas.
个性化医疗和医疗保健改革为病理学家在患者护理中提供了更核心和更显著的角色。病理学家面临着对组织标本进行临床和研究检测的新的、更复杂的要求，包括对体细胞和遗传性突变的检测。病理学家必须理解分子检测的应用和要求，以及在处理用于临床和研究目的的组织请求时的法律和伦理责任，以最好地满足患者和临床医生的需求，并遵守联邦和州法律。本文综述了这些快速发展且复杂的领域。
