Jattan Rakesh, De Silva Harsha L, De Silva Rohana Kumara, Rich Alison M, Love Robert M
Department of Oral Diagnostic and Surgical Sciences, University of Otago, Dunedin, New Zealand.
N Z Dent J. 2011 Dec;107(4):112-6.
To report on the clinicopathological aspects of odontogenic keratocysts (OKC)/keratocystic odontogenic tumours (KCOT) presenting in a New Zealand population.
Information on defined areas--including age at presentation, gender, anatomical sub-location, presenting features, histological subtype and the recurrence pattern--were extracted from the histopathological data available in the Oral Pathology database of the University of Otago School of Dentistry.
Two hundred and twenty three cases of OKC/ KCOT were identified over the period ranging from 1987 to 2008. Mean age at presentation was 37.0 years (males 38.6 years, females 34.4 years), with 61.0% of cases being male. The mandible was the dominant jaw affected, with 65.9% of lesions, with the angle of mandible being the commonest anatomical sub-location (with 32.4% of lesions). One-fifth of the cases were asymptomatic incidental findings, while the majority of problems were related to the third molar tooth and/or pain and swelling. The overall recurrence rate was 18.3%, with the majority (62.2%) in the mandible and more males (67.5%) affected. Recurrence was highest in the first 5 years of follow-up, and decreased sharply thereafter.
This study is the first to describe the frequency, distribution, presentation and recurrence rates of OKC/KCOT in New Zealand and shows that these are similar to those reported from other populations.
报告新西兰人群中牙源性角化囊肿（OKC）/角化囊性牙源性肿瘤（KCOT）的临床病理特征。
从奥塔哥大学牙科学院口腔病理学数据库中的组织病理学数据中提取有关特定区域的信息，包括就诊年龄、性别、解剖亚部位、临床表现、组织学亚型和复发模式。
在1987年至2008年期间共识别出223例OKC/KCOT病例。就诊时的平均年龄为37.0岁（男性38.6岁，女性34.4岁），61.0%的病例为男性。下颌骨是受影响的主要颌骨，占病变的65.9%，下颌角是最常见的解剖亚部位（占病变的32.4%）。五分之一的病例是无症状的偶然发现，而大多数问题与第三磨牙以及疼痛和肿胀有关。总体复发率为18.3%，大多数复发（62.2%）发生在下颌骨，且男性受影响更多（67.5%）。复发率在随访的前5年最高，此后急剧下降。
本研究首次描述了新西兰OKC/KCOT的发病率、分布、临床表现和复发率，并表明这些与其他人群报告的情况相似。
