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克罗地亚成年人群中心血管行为危险因素与死亡率的关联:克罗地亚队列研究(CroHort研究)

Association of behavioral cardiovascular risk factors with mortality in Croatian adult population: the CroHort study.

作者信息

Sović Slavica, Vitale Ksenija, Brborović Ognjen, Dzakula Aleksandar, Tiljak Hrvoje

机构信息

University of Zagreb, School of Medicine, "Andrija Stampar" School of Public Health, Zagreb, Croatia.

出版信息

Coll Antropol. 2012 Jan;36 Suppl 1:177-82. doi: 10.5671/ca.2012361s.177.

DOI:10.5671/ca.2012361s.177
PMID:22338768
Abstract

This study examined individual and combined influence of smoking, physical inactivity, alcohol drinking, and unhealthy diet on total mortality. Relationship between individual and combined poor health behaviours and total mortality were examined using Cox proportional hazards regression. Out of 7490 individuals included in the study, during 5 years follow up 808 died. Adjusted hazard ratios (HRs), and 95% confidence intervals (95% CIs) for men with health behaviour scores 1, 2, 3, and 4 compared with those with score 0 were 1.67 (1.24-2.24), 2.28 (1.64-3.18), 2.24 (1.32-3.84), and 2.86 (0.77-11.70), respectively (p value for trend < 0.001). Adjusted HRs (95% CIs) for women with health behaviour scores 1, 2, and 3 compared with those with score 0 were 1.17 (0.97-1.42), 1.37 (1.02-1.86), and 1.20 (0.37-3.61), respectively (p value for trend = 0.04). A unit of the health behaviour score increased mortality risk equivalent to being 5.9 and 2.9 years older, for man and woman respectively.

摘要

本研究考察了吸烟、缺乏身体活动、饮酒和不健康饮食对总死亡率的个体影响及综合影响。使用Cox比例风险回归分析了个体及综合不良健康行为与总死亡率之间的关系。在纳入研究的7490名个体中,5年随访期间有808人死亡。健康行为得分分别为1、2、3和4的男性与得分为0的男性相比,调整后的风险比(HRs)及95%置信区间(95% CIs)分别为1.67(1.24 - 2.24)、2.28(1.64 - 3.18)、2.24(1.32 - 3.84)和2.86(0.77 - 11.70)(趋势p值<0.001)。健康行为得分分别为1、2和3的女性与得分为0的女性相比,调整后的HRs(95% CIs)分别为1.17(0.97 - 1.42)、1.37(1.02 - 1.86)和1.20(0.37 - 3.61)(趋势p值 = 0.04)。健康行为得分每增加一个单位,男性和女性的死亡风险分别相当于年龄增加5.9岁和2.9岁。

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