Department of Biochemistry and Molecular Medicine, Lomonosov Moscow State University, Moscow, Russia.
Biochemistry (Mosc). 2011 Dec;76(13):1528-55. doi: 10.1134/S0006297911130104.
This review focuses on basic principles of motility in different cell types, formation of the specific cell structures that enable directed migration, and how external signals are transduced into cells and coupled to the motile machinery. Feedback mechanisms and their potential role in maintenance of internal chemotactic gradients and persistence of directed migration are highlighted.
这篇综述重点介绍了不同细胞类型中运动的基本原理、形成能够进行定向迁移的特定细胞结构的方式，以及外部信号如何被转导到细胞中并与运动机制偶联。还强调了反馈机制及其在维持内部趋化梯度和保持定向迁移方面的潜在作用。
