Hoogendoorn D
Landelijke Medische Registratie-Stichting Informatiecentrum voor de Gezondheidszorg, Utrecht.
Ned Tijdschr Geneeskd. 1990 Oct 20;134(42):2034-8.
In the last 40 years the national mortality from melanoma of the skin, corrected for age, has increased by over 300%. Figures for males are always higher than those for females and this difference tends to grow larger. Since 1960 it has mostly been the mortality in the age groups 30-69 years that increased. The rise in mortality of older persons has been relatively small. Among the patients treated clinically, females are in the majority and increasingly so from year to year. Probability of survival is better for females than for males. Major shifts seem to occur in the localization of the lesion. Lesions are localized relatively less often in the skin of the head. In males, it is the frequency of melanomas of the trunk that is rising, while melanomas of the extremities are markedly increasing in frequency in both males and females.
在过去40年中，经年龄校正后的全国皮肤黑色素瘤死亡率增长了300%以上。男性的死亡率一直高于女性，且这种差异有扩大趋势。自1960年以来，主要是30 - 69岁年龄组的死亡率上升。老年人死亡率的上升幅度相对较小。在接受临床治疗的患者中，女性占多数，且逐年增多。女性的生存概率优于男性。病变的部位似乎发生了重大变化。病变位于头部皮肤的情况相对较少。在男性中，躯干黑色素瘤的发病率在上升，而在男性和女性中，四肢黑色素瘤的发病率都在显著增加。
