伯氏疏螺旋体培养物的抗肿瘤活性。
Antitumor activity of Borrelia burgdorferi cultures.
作者信息
Oravec C, Kmety E
机构信息
Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
出版信息
Neoplasma. 1990;37(5):595-9.
PMID:2234219
Abstract
Cultures of B. burgdorferi, their supernatants as well as washed cells revealed in vitro a considerable antitumor activity against cells of Gardner lymphoma. Németh-Kellner lymphoma and LP-2 plasmacytoma. In in vivo tests an inhibition of tumor growth was evident, even if the treatment was started on day 4 after implantation of the tumor. The best results were obtained with the supernatants of the cultures.
摘要
伯氏疏螺旋体的培养物、其培养上清液以及洗涤后的细胞在体外显示出对加德纳淋巴瘤细胞、内梅特-凯尔纳淋巴瘤细胞和LP-2浆细胞瘤细胞具有相当大的抗肿瘤活性。在体内试验中，即使在肿瘤植入后第4天开始治疗，肿瘤生长的抑制也很明显。培养上清液取得了最佳结果。
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