School of Biomedical Engineering, Capital Medical University, Beijing 100069, PR China.
Int J Psychophysiol. 2012 Jun;84(3):233-9. doi: 10.1016/j.ijpsycho.2012.01.021. Epub 2012 Feb 15.
Simultaneous EEG-fMRI is a non-invasive investigation technique developed to localize the generators of interictal epileptiform discharges (IED) in patients with epilepsy. Although the value of EEG-fMRI in epilepsy presurgical evaluation is being assessed clinically, its utility is still controversial. In this review, we considered EEG-fMRI applications in epilepsy presurgical evaluation with a focus on validation studies that compared the results of EEG-fMRI with those of the current "gold standard" intracranial EEG (icEEG) in order to assess its utility of seizure focus localization and the possibility for EEG-fMRI to reduce the need for invasive techniques such as icEEG. Since the advances of EEG-fMRI partially rely on the maturation of its data analysis, we also reviewed the methodological developments in EEG-fMRI analysis. It is possible that combining with other neuroimaging modalities such as MEG/MSI and ESI, EEG-fMRI may play a greater role in epilepsy presurgical evaluation.
同步 EEG-fMRI 是一种非侵入性的研究技术，旨在定位癫痫患者的发作间期癫痫样放电（IED）的起源。尽管 EEG-fMRI 在癫痫术前评估中的价值正在临床评估中，但它的实用性仍存在争议。在这篇综述中，我们考虑了 EEG-fMRI 在癫痫术前评估中的应用，重点是比较 EEG-fMRI 结果与当前“金标准”颅内 EEG（icEEG）的验证研究，以评估其对致痫灶定位的实用性以及 EEG-fMRI 降低对侵入性技术（如 icEEG）的需求的可能性。由于 EEG-fMRI 的进展部分依赖于数据分析的成熟度，我们还回顾了 EEG-fMRI 分析方法的发展。结合其他神经影像学模式，如 MEG/MSI 和 ESI，EEG-fMRI 可能在癫痫术前评估中发挥更大的作用。
