Alfred University, Inamori School of Engineering, Alfred, NY 14802, USA.
Acta Biomater. 2012 Jul;8(6):2324-30. doi: 10.1016/j.actbio.2012.02.009. Epub 2012 Feb 13.
The compositional palette traditionally used to develop bioactive glasses has grown in recent times to include therapeutic inorganic species such as zinc and strontium. Historical regression models used for predicting the properties of bioactive glasses as a function of composition have not evolved to consider this expanded compositional space. In this work, nonlinear regression analysis was applied to historical data to construct predictive models for the glass transition temperature and the coefficient of thermal expansion of next-generation bioactive glasses. The new regression models also provide some degree of improvement over existing models in predicting the properties of traditional bioactive glasses.
近年来,用于开发生物活性玻璃的组成色板已扩展到包括锌和锶等治疗性无机物质。用于预测生物活性玻璃性能随组成变化的历史回归模型尚未发展到考虑这种扩展的组成空间。在这项工作中,非线性回归分析应用于历史数据,以构建下一代生物活性玻璃的玻璃化转变温度和热膨胀系数的预测模型。新的回归模型在预测传统生物活性玻璃的性能方面也提供了一定程度的改进。