Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA.
Gerontology. 2012;58(4):331-6. doi: 10.1159/000334242. Epub 2012 Feb 16.
Prostate cancer, like many diseases, is more common in older men. Although an estimated 1 in 7 men will be diagnosed with it, the majority of these men will not die from prostate cancer. The latent nature of this disease, the use of screening with prostate-specific antigen (PSA) testing and the greater risk of dying from causes other than prostate cancer contribute to this disparity. As the US population continues to age, prostate cancer screening and disease management presents an increasingly important public health issue. We discuss the current PSA screening recommendations and practices in the USA and the benefits and harms of screening older populations.
前列腺癌与许多疾病一样，在老年男性中更为常见。尽管估计每 7 名男性中就有 1 名被诊断患有前列腺癌，但这些男性中的大多数不会死于前列腺癌。这种疾病的潜伏性、使用前列腺特异性抗原 (PSA) 检测进行筛查以及死于前列腺癌以外原因的风险增加，导致了这种差异。随着美国人口的持续老龄化，前列腺癌筛查和疾病管理成为一个日益重要的公共卫生问题。我们讨论了美国目前的 PSA 筛查建议和实践，以及对老年人群进行筛查的益处和危害。
