Samanta S K, Fariduddin K, Mahapatra N, Bhunia J, Mondal P
Calcutta National Medical College and Hospital, West Bengal, India.
Nepal J Ophthalmol. 2012 Jan-Jun;4(1):162-4. doi: 10.3126/nepjoph.v4i1.5868.
Hooch blindness following consumption of adulterated alcohol has been known for centuries.
To study cases of mass alcohol intoxication followed by Hooch blindness in eastern India.
Ten patients of toxic amblyopia collected from a community mass intoxication following consumption of adulterated alcohol were studied. The parameters studied were the findings of ocular examination, applanation tonometry, automated perimetry and visual-evoked potential (VEP). As a part of the special investigations fundus photography and OCT were done. Routine blood examination, fasting lipid profile, postprandial blood sugar estimation were done . All patients were treated with injections of methyl prednisolone and Hydroxy cobalamine, antioxidants and local neuro-protective agents.
Along with diminished vision (from NPL to 3/60), marked pallor of the disc without any other retinal change were noted. The amplitude on VEP was significantly reduced. However, visual improvement (up to 6/18) in 7 patients was observed within 6 weeks of treatment.
Hooch blindness in India can be prevented by creating awareness among the target population and reducing the cost of country liquor.
饮用掺假酒精导致的酒精性盲已经存在了几个世纪。
研究印度东部因大量酒精中毒继发酒精性盲的病例。
对10例因饮用掺假酒精导致群体中毒而出现中毒性弱视的患者进行了研究。研究参数包括眼部检查、压平眼压测量、自动视野检查和视觉诱发电位（VEP）的结果。作为特殊检查的一部分，进行了眼底摄影和光学相干断层扫描（OCT）。进行了常规血液检查、空腹血脂谱、餐后血糖测定。所有患者均接受甲基泼尼松龙和甲钴胺注射、抗氧化剂及局部神经保护剂治疗。
除视力下降（从无光感到3/60）外，还发现视盘明显苍白，无其他视网膜改变。VEP的波幅明显降低。然而，7例患者在治疗6周内视力得到改善（提高到6/18）。
通过提高目标人群的意识和降低国产酒的成本，可以预防印度的酒精性盲。
