Department of Cardiovascular Surgery, Hospital Hietzing, Vienna, Austria.
Eur J Cardiothorac Surg. 2012 Sep;42(3):571-6. doi: 10.1093/ejcts/ezs056. Epub 2012 Feb 15.
The goal of the retrospective study was to relate the site of the primary entry tear in acute type B aortic dissections to the presence or development of complications.
A consecutive series of 52 patients referred with acute type B aortic dissection was analysed with regard to the location of the primary entry tear (convexity or concavity of the distal aortic arch) using the referral CT scans at the time of diagnosis. These findings were related to the clinical outcome as well as to the need for intervention.
Twenty-five patients (48%) had the primary entry tear located at the convexity of the distal aortic arch, whereas 27 patients (52%) had the primary entry tear located at the concavity of the distal aortic arch. Twenty per cent of patients with the primary entry tear at the convexity presented with or developed complications, whereas 89% had or developed complications with the primary entry tear at the concavity (P < 0.001). Furthermore, in patients with complicated type B aortic dissection, the distance of the primary entry tear to the left subclavian artery was significantly shorter as in uncomplicated patients (8 vs. 21 mm; P = 0.002). In Cox regression analysis, a primary entry tear at the concavity of the distal aortic arch was identified as an independent predictor of the presence or the development of complicated type B aortic dissection.
A primary entry tear at the concavity of the aortic arch as well as a short distance between the primary entry tear and the left subclavian artery are frequently associated with the presence or the development of complicated acute type B aortic dissection. These findings shall help us to further differentiate acute type B aortic dissections in addition to the common categorization in complicated and uncomplicated. These findings may therefore also have an impact on primary treatment.
本回顾性研究旨在探讨急性 B 型主动脉夹层原发破口部位与并发症发生或发展的关系。
对 52 例急性 B 型主动脉夹层患者的连续病例系列进行分析,根据诊断时的转诊 CT 扫描,分析原发破口(降主动脉远端凸面或凹面)的位置。这些发现与临床结果以及干预需求有关。
25 例(48%)患者的原发破口位于降主动脉远端凸面,27 例(52%)患者的原发破口位于降主动脉远端凹面。凸面原发破口的 20%患者出现或发展为并发症,而凹面原发破口的 89%患者出现或发展为并发症(P < 0.001)。此外,在并发 B 型主动脉夹层的患者中,原发破口距左锁骨下动脉的距离明显短于未并发患者(8 毫米对 21 毫米;P = 0.002)。在 Cox 回归分析中,降主动脉远端凹面的原发破口被确定为并发 B 型主动脉夹层存在或发展的独立预测因子。
主动脉弓凹面的原发破口以及原发破口与左锁骨下动脉之间的短距离与并发或进展的急性 B 型主动脉夹层密切相关。这些发现有助于我们进一步区分急性 B 型主动脉夹层,除了常见的复杂和非复杂分类。这些发现可能会对原发治疗产生影响。