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强迫症作为维生素B12缺乏的早期表现。

Obsessive compulsive disorder as early manifestation of B12 deficiency.

作者信息

Valizadeh Maryam, Valizadeh Nasim

机构信息

Department of Family Medicine, General Practitioner, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Indian J Psychol Med. 2011 Jul;33(2):203-4. doi: 10.4103/0253-7176.92051.

DOI:10.4103/0253-7176.92051
PMID:22345852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3271502/
Abstract

B12 acts as a cofactor in synthesis of neurotransmitters such as serotonin and dopamine, thus B12 deficiency affects mood, emotions and sleeping and can lead to psychiatric disorders. Psychiatric manifestations of B12 deficiency are varied. They seldom precede anemia. We want to present a case of B12 deficiency which was presented with obsessive compulsive disorder.

摘要

维生素B12作为血清素和多巴胺等神经递质合成中的一种辅助因子，因此维生素B12缺乏会影响情绪、情感和睡眠，并可能导致精神障碍。维生素B12缺乏的精神表现多种多样。它们很少先于贫血出现。我们想介绍一例以强迫症为表现的维生素B12缺乏病例。

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1
Obsessive compulsive disorder as early manifestation of B12 deficiency.强迫症作为维生素B12缺乏的早期表现。
Indian J Psychol Med. 2011 Jul;33(2):203-4. doi: 10.4103/0253-7176.92051.
2
[Psychiatric manifestations of vitamin B12 deficiency: a case report].[维生素B12缺乏的精神症状：一例报告]
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Vitamin B12 and folic acid serum levels in obsessive compulsive disorder.强迫症患者血清中维生素B12和叶酸水平
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Obsessive Compulsive Disorder due to B12 Deficiency: Justification Required.维生素B12缺乏所致强迫症：需要提供理由。
Indian J Psychol Med. 2012 Jul;34(3):298-9. doi: 10.4103/0253-7176.106045.

本文引用的文献

1
Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder.更新的关于 5-羟色胺能系统在强迫症中假设作用的综述。
Neuropsychiatr Dis Treat. 2005 Sep;1(3):231-43.
2
Vitamin b₁₂ deficiency manifested as mania: a case report.维生素B₁₂缺乏表现为躁狂：一例报告
Prim Care Companion J Clin Psychiatry. 2007;9(3):238. doi: 10.4088/pcc.v09n0311g.
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[Postoperative dementia: toxicity of nitrous oxide].[术后痴呆：氧化亚氮的毒性]
Encephale. 2007 Jan-Feb;33(1):95-7. doi: 10.1016/s0013-7006(07)91563-8.
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[Psychiatric manifestations of vitamin B12 deficiency: a case report].[维生素B12缺乏的精神症状：一例报告]
Encephale. 2003 Nov-Dec;29(6):560-5.
5
Is there a common mechanism of serotonin dysregulation in anorexia nervosa and obsessive compulsive disorder?神经性厌食症和强迫症中血清素失调是否存在共同机制？
Eat Weight Disord. 2002 Sep;7(3):221-31. doi: 10.1007/BF03327460.
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J Psychiatry Neurosci. 1998 May;23(3):179-80.
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Folate and cobalamin in psychiatric illness.精神疾病中的叶酸和钴胺素
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Eating disorder and obsessive-compulsive disorder: neurochemical and phenomenological commonalities.饮食失调与强迫症：神经化学和现象学上的共性
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9
Organic psychosis without anemia or spinal cord symptoms in patients with vitamin B12 deficiency.维生素B12缺乏患者出现无贫血或脊髓症状的器质性精神病。
Am J Psychiatry. 1983 Feb;140(2):218-21. doi: 10.1176/ajp.140.2.218.
10
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.在无贫血或大细胞症情况下由钴胺素缺乏引起的神经精神障碍。
N Engl J Med. 1988 Jun 30;318(26):1720-8. doi: 10.1056/NEJM198806303182604.