Dow G C, Chow A W
Division of Infectious Diseases, Department of Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, British Columbia.
Can J Infect Dis. 1992 Nov;3(6):315-8. doi: 10.1155/1992/985398.
Two cases of lung abscess, in which Legionella species were identified in association with other bacterial isolates, are presented. In the first case, Legionella pneumophila and Klebsiella pneumoniae were identified in a 24-year-old post renal transplant patient with a right upper lobe pulmonary abscess. Healing did not occur until the institution of specific therapy directed against legionella. In the second case, Legionella micdadei and several other respiratory bacterial pathogens were identified in a 74-year-old woman with a lung abscess. The patient later died with multisystem failure despite adequate antimicrobial therapy. Prior cases of legionella-associated lung abscess have occurred predominantly in corticosteroid-treated patients. The role of coexisting bacterial isolates remains obscure.
本文报告了两例肺脓肿病例,其中军团菌属与其他细菌分离株同时被鉴定出来。第一例中,在一名24岁的肾移植术后患者的右上叶肺脓肿中鉴定出嗜肺军团菌和肺炎克雷伯菌。直到针对军团菌采取特异性治疗后,病情才得以好转。第二例中,在一名74岁患有肺脓肿的女性患者中鉴定出米克戴德军团菌和其他几种呼吸道细菌病原体。尽管进行了充分的抗菌治疗,该患者后来仍死于多系统功能衰竭。先前与军团菌相关的肺脓肿病例主要发生在接受皮质类固醇治疗的患者中。共存细菌分离株的作用仍不明确。