Dowling J N, Kroboth F J, Karpf M, Yee R B, Pasculle A W
Am Rev Respir Dis. 1983 Jan;127(1):121-5. doi: 10.1164/arrd.1983.127.1.121.
An immunocompromised patient developed pneumonia in which both Legionella micdadei and L. pneumophila, serogroup 6, were isolated from transtracheal aspirates in the absence of any other bacteria. Unusual features included the development of disseminated intravascular coagulation and multiple pulmonary abscesses during treatment with erythromycin, and relapse of the legionellosis after extended therapy with both erythromycin and rifampin, which was heralded by septic shock. Because simultaneous infection with two distinct species of Legionella occurs, concurrent increases in antibody titer to more than one Legionella may, in some instances, reflect multiple infection rather than cross-reacting antibody.
一名免疫功能低下的患者发生了肺炎,在经气管抽吸物中分离出米克戴德军团菌和嗜肺军团菌血清群6,未发现任何其他细菌。不寻常的特征包括在使用红霉素治疗期间发生弥散性血管内凝血和多发性肺脓肿,以及在使用红霉素和利福平进行延长治疗后军团菌病复发,并伴有感染性休克。由于出现了两种不同军团菌的同时感染,在某些情况下,针对多种军团菌的抗体滴度同时升高可能反映的是多重感染而非交叉反应抗体。