Langley J M, Ford-Jones E L, Armstrong D C, Gold R, Read S, Levison H
Department of Pediatrics. Divisions of Infectious Diseases. Pulmonary Medicine, and the Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Ontario.
Can J Infect Dis. 1993 Jul;4(4):229-31. doi: 10.1155/1993/829573.
A 19-year-old immunocompetent cystic fibrosis patient with recurrent neck abscesses due to a multiresistant Pseudomonas cepacia is described. After 13 drainage procedures over a two-year period, a trial of interferon-gamma therapy to enhance monocyte function was attempted. The patient had one minor recurrence but has otherwise been symptom free for almost two years. P cepacia is an unusual cause of extrapulmonary abscess formation. Such abscesses may not present with classical signs of inflammation, are likely to be multiresistant and to require surgical drainage. Immunotherapy may be justified in the immunocompetent host when infection is refractory to medical and surgical therapy.
本文描述了一名19岁免疫功能正常的囊性纤维化患者,因多重耐药洋葱伯克霍尔德菌反复出现颈部脓肿。在两年内进行了13次引流手术后,尝试采用γ干扰素疗法来增强单核细胞功能。该患者有一次轻微复发,除此之外几乎两年无症状。洋葱伯克霍尔德菌是肺外脓肿形成的不常见病因。此类脓肿可能不表现出典型的炎症体征,可能具有多重耐药性,需要手术引流。当感染对药物和手术治疗均无效时,免疫疗法对于免疫功能正常的宿主可能是合理的。