Zuckier L S, Finkelstein M, Kreutzer E R, Stone P L, Freed S Z, Bard R H, Blaufox M D, Freeman L M
Department of Nuclear Medicine, Montefiore Medical Center, Bronx, New York.
Nucl Med Commun. 1990 Sep;11(9):589-96. doi: 10.1097/00006231-199009000-00002.
Laterality of prostatic lymphatic drainage was successfully assessed in nine patients with prostatic carcinoma after direct unilateral transrectal injections of 99Tcm-antimony sulphide colloid by Franzen needle. Pelvic lymphatic drainage was equally divided between ipsilateral, contralateral and bilateral patterns. The frequent observation of radiocolloid migration to contralateral lymph node groups in patients with prostate carcinoma, including those with primary disease localized clinically to a single lobe of the prostate, indicates the potential for contralateral pelvic lymph node metastases in this population. This finding may be important in determining the appropriate surgical staging and treatment of patients with prostate carcinoma. The clinical applicability of lymphoscintigraphy in the evaluation of metastatic spread and in lymph node biopsy planning requires further study.
通过Franzen针经直肠直接单侧注射99Tcm-硫化锑胶体后，成功评估了9例前列腺癌患者前列腺淋巴引流的侧别情况。盆腔淋巴引流在同侧、对侧和双侧模式之间平均分布。在前列腺癌患者中，包括那些临床原发性疾病局限于前列腺单叶的患者，经常观察到放射性胶体迁移至对侧淋巴结组，这表明该人群存在对侧盆腔淋巴结转移的可能性。这一发现对于确定前列腺癌患者合适的手术分期和治疗可能很重要。淋巴闪烁显像在评估转移扩散和淋巴结活检规划中的临床适用性需要进一步研究。
