4-羟基-3,5-二甲氧基-N-{4-[(5-甲基-1,2-恶唑-3-基)氨磺酰基]苯基}苯甲酰胺甲醇单溶剂合物
4-Hy-droxy-3,5-dimeth-oxy-N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamo-yl]phen-yl}benzamide methanol monosolvate.
作者信息
Pan Wei-Gao, Zhao Zhi-Dong, Luo Peng, Lin Cui-Wu, Miao Jian-Hua
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o379. doi: 10.1107/S1600536811055991. Epub 2012 Jan 14.
Abstract
The title compound, C(19)H(19)N(3)O(7)S·CH(3)OH, was synthesized from syringic acid and sulfamethoxazole. The benzene rings make a dihedral angle of 41.8 (1)° and the isoxazole ring is twisted by 74.3 (1)° from the central benzene ring. The crystal packing features O-H⋯O and O-H⋯N hydrogen bonds in which the hy-droxy groups from the main mol-ecule and methanol solvent mol-ecules serve as donor groups.
摘要
标题化合物C(19)H(19)N(3)O(7)S·CH(3)OH由丁香酸和磺胺甲恶唑合成。苯环间的二面角为41.8 (1)°，异恶唑环与中心苯环扭转74.3 (1)°。晶体堆积具有O-H⋯O和O-H⋯N氢键，其中主分子和甲醇溶剂分子中的羟基作为供体基团。
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