Koulaouzidis Anastasios, Douglas Sarah, Plevris John N
Anastasios Koulaouzidis, Sarah Douglas, John N Plevris, Endoscopy Unit, Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, Scotland, United Kingdom.
World J Gastrointest Endosc. 2012 Feb 16;4(2):33-7. doi: 10.4253/wjge.v4.i2.33.
To check the usefulness of blue mode (BM) review in lewis score (LS) calculation, by comparing it with respective LS results obtained by white light (WL) small-bowel capsule endoscopy (SBCE) review and mucosal inflammation as reflected by faecal calprotectin (FC) levels, considered as 'gold standard' for this study.
Computational analysis of our SBCE database to identify patients who underwent SBCE with PillCam(®) and had FC measured within a 30-day period from their test. Only patients with prior colonoscopy were included, to exclude any colon pathology-associated FC rise. Each small bowel tertile was reviewed (viewing speed 8 fps) with WL and BM, in a back-to-back mode, by a single experienced reviewer. LS were calculated after each WL and BM reviews. Pearson rank correlation (rho, r) statistic was applied.
Twenty-seven (n = 27, 20F/7M) patients were included. Thirteen (n = 13) had SBCE with PillCam(®)SB1, and the remainder (n = 14) with PillCam(®)SB2. The median level of FC in this cohort was 125 μg/g. LS (calculated in WL SBCE review) correlation with FC levels was r = 0.490 (P = 0.01), while for BM review and LS correlation with FC was r = 0.472 (P = 0.013).
Although BM is believed to enhance mucosal details i.e., small mucosal breaks, it did not perform better than WL in the calculation of LS in our cohort.
通过将蓝光模式（BM）检查与白光（WL）小肠胶囊内镜检查（SBCE）获得的相应Lewis评分（LS）结果以及粪便钙卫蛋白（FC）水平反映的黏膜炎症进行比较，来检验BM检查在LS计算中的实用性，FC水平在本研究中被视为“金标准”。
对我们的SBCE数据库进行计算分析，以确定接受PillCam（®）小肠胶囊内镜检查且在检查后30天内测量了FC的患者。仅纳入先前接受过结肠镜检查的患者，以排除任何与结肠病理相关的FC升高。由一位经验丰富的审阅者以背对背模式对每个小肠三分位数进行WL和BM检查（查看速度为8帧/秒）。在每次WL和BM检查后计算LS。应用Pearson等级相关性（rho，r）统计量。
纳入了27名患者（n = 27，20名女性/7名男性）。13名患者（n = 13）接受了PillCam（®）SB1小肠胶囊内镜检查，其余患者（n = 14）接受了PillCam（®）SB2检查。该队列中FC的中位数水平为125μg/g。LS（在WL SBCE检查中计算）与FC水平的相关性为r = 0.490（P = 0.01），而对于BM检查，LS与FC的相关性为r = 0.472（P = 0.013）。
尽管BM被认为可增强黏膜细节，即小的黏膜破损，但在我们的队列中，其在LS计算中的表现并不优于WL。
