Suckling Rebecca, Gallagher Hugh
South West Thames Renal and Transplantation Unit, St. Helier Hospital, Carshalton, Surrey, UK.
J Ren Care. 2012 Feb;38 Suppl 1:4-11. doi: 10.1111/j.1755-6686.2012.00274.x.
The prevalence of chronic kidney disease (CKD) and diabetes mellitus (DM) is increasing worldwide. CKD and diabetes are important risk factors for cardiovascular disease and all three conditions are key components of the multiple morbidities increasingly evident as population age in the developed world. Shared risk factors, both traditional and nontraditional, contribute to these associations, and are important targets for public health and both primary and secondary care. Prevention and early detection in combination with a holistic approach to vascular care will be key to improving outcomes and reducing costs. Routine reporting of estimated glomerular filtration rate to aid early identification, risk stratification through quantitative proteinuria testing, appropriate use of renin-angiotensin system antagonists and optimal blood pressure control are important strategies to improve the care of people with or at risk of CKD.
慢性肾脏病（CKD）和糖尿病（DM）在全球范围内的患病率正在上升。CKD和糖尿病是心血管疾病的重要危险因素，而这三种疾病都是随着发达国家人口老龄化日益明显的多种疾病的关键组成部分。传统和非传统的共同危险因素促成了这些关联，并且是公共卫生以及初级和二级保健的重要目标。预防和早期检测与全面的血管护理方法相结合，将是改善治疗效果和降低成本的关键。常规报告估计肾小球滤过率以帮助早期识别，通过定量蛋白尿检测进行风险分层，合理使用肾素-血管紧张素系统拮抗剂以及优化血压控制，是改善CKD患者或有CKD风险人群护理的重要策略。
