Lai Ai-Ping, Chen Wen-He
Physical Education Department of Zhejiang College of Sports, Hangzhou 311231, China.
Sheng Li Xue Bao. 2012 Feb 25;64(1):96-100.
Visfatin, also named nicotinamide phosphoribosyl transferase (NAMPT), is a cytokine secreted from adipose tissue. Visfatin can regulate immune action and is involved in the NAD+ salvage pathway. In addition, recent researches have shown that visfatin helps the regulation of glucose and lipid metabolism, especially in exercise-induced weight reduction for obesity. The aim of this review is to provide an overview of the contribution of visfatin gene polymorphisms to glucose and lipid metabolism and exercise-induced weight reduction in obesity.
内脂素，也称为烟酰胺磷酸核糖转移酶（NAMPT），是一种从脂肪组织分泌的细胞因子。内脂素可以调节免疫作用，并参与NAD+补救途径。此外，最近的研究表明，内脂素有助于调节葡萄糖和脂质代谢，特别是在运动诱导的肥胖症体重减轻方面。本综述的目的是概述内脂素基因多态性对肥胖症中葡萄糖和脂质代谢以及运动诱导的体重减轻的作用。
