Department of Functional Brain Imaging, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai 980-8575, Japan.
Soc Cogn Affect Neurosci. 2013 Jun;8(5):515-22. doi: 10.1093/scan/nss025. Epub 2012 Feb 20.
Our impressions of other people are formed mainly from the two possible factors of facial attractiveness and trustworthiness. Previous studies have shown the importance of orbitofrontal-hippocampal interactions in the better remembering of attractive faces, and psychological data have indicated that faces giving an impression of untrustworthiness are remembered more accurately than those giving an impression of trustworthiness. However, the neural mechanisms of the latter effect are largely unknown. To investigate this issue, we investigated neural activities with event-related fMRI while the female participants rated their impressions of the personalities of men in terms of trustworthiness. After the rating, memory for faces was tested to identify successful encoding activity. As expected, faces that gave bad impressions were remembered better than those that gave neutral or good impressions. In fMRI data, right insular activity reflected an increasing function of bad impressions, and bilateral hippocampal activities predicted subsequent memory success. Additionally, correlation between these insular and hippocampal regions was significant only in the encoding of faces associated with a bad impression. Better memory for faces associated with an impression of bad personality could reflect greater interaction between the avoidance-related insular region and the encoding-related hippocampal region.
面部吸引力和可信度。先前的研究表明，眶额-海马相互作用在更好地记忆有吸引力的面孔方面很重要，而心理数据表明，给人不可信印象的面孔比给人可信印象的面孔被记得更准确。然而，后者的神经机制在很大程度上是未知的。为了研究这个问题，我们使用事件相关 fMRI 来调查神经活动，同时让女性参与者根据可信度来评价男性的个性印象。在评价之后，对面孔的记忆进行了测试，以确定成功的编码活动。正如预期的那样，给人不良印象的面孔比给人中性或良好印象的面孔记得更好。在 fMRI 数据中，右岛叶活动反映了不良印象的递增函数，双侧海马活动预测了随后的记忆成功。此外，这些岛叶和海马区域之间的相关性仅在与不良印象相关的面孔的编码中显著。与不良个性印象相关的面孔的更好记忆可能反映了回避相关的岛叶区域和与编码相关的海马区域之间更大的相互作用。
