Division of Musculoskeletal Physiotherapy, Department of Health Sciences, Artesis University College Antwerp, Van Aertselaerstraat 31, Merksem, Antwerp, Belgium.
Clin Rheumatol. 2012 Jun;31(6):921-9. doi: 10.1007/s10067-012-1946-z. Epub 2012 Feb 16.
In addition to fatigue, many patients with chronic fatigue syndrome (CFS) experience chronic musculoskeletal pain. We aimed at examining the role of catastrophizing, coping, kinesiophobia, and depression in the chronic pain complaints and in the daily functioning of CFS patients. A consecutive sample of 103 CFS patients experiencing chronic widespread musculoskeletal pain completed a battery of questionnaires evaluating pain, daily functioning, and psychological characteristics (depression, kinesiophobia, pain coping, and catastrophizing). Thirty-nine patients participated in the 6-12-month follow-up, consisting of questionnaires evaluating pain and pressure pain algometry. Correlation and linear regression analyses were performed to identify predictors. The strongest correlations with pain intensity were found for catastrophizing (r = -.462, p < .001) and depression (r = -.439, p < .001). The stepwise multiple regression analysis revealed that catastrophizing was both the immediate main predictor for pain (20.2%) and the main predictor on the longer term (20.1%). The degree of depression was responsible for 10% in the observed variance of the VAS pain after 6-12 months. No significant correlation with pain thresholds could be revealed. The strongest correlations with daily functioning at baseline were found for catastrophizing (r = .435, p < .001) and depression (r = .481, p < .001). Depression was the main predictor for restrictions in daily functioning (23.1%) at baseline. Pain catastrophizing and depression were immediate and long-term main predictors for pain in patients with CFS having chronic widespread musculoskeletal pain. They were also correlated to daily functioning, with depression as the main predictor for restrictions in daily functioning at baseline.
除了疲劳，许多慢性疲劳综合征（CFS）患者还会经历慢性肌肉骨骼疼痛。我们旨在研究灾难化、应对、运动恐惧症和抑郁在 CFS 患者慢性疼痛主诉和日常功能中的作用。连续的 103 名患有慢性广泛性肌肉骨骼疼痛的 CFS 患者完成了一系列评估疼痛、日常功能和心理特征（抑郁、运动恐惧症、疼痛应对和灾难化）的问卷。39 名患者参加了 6-12 个月的随访，包括评估疼痛和压痛压痛的问卷。进行了相关和线性回归分析以确定预测因子。与疼痛强度相关性最强的是灾难化（r = -.462，p <.001）和抑郁（r = -.439，p <.001）。逐步多元回归分析显示，灾难化既是疼痛的即时主要预测因素（20.2%），也是长期的主要预测因素（20.1%）。抑郁程度对 6-12 个月后 VAS 疼痛的可观察方差负责 10%。与疼痛阈值无显著相关性。与基线时日常功能相关性最强的是灾难化（r = -.435，p <.001）和抑郁（r = -.481，p <.001）。抑郁是基线时日常功能受限的主要预测因素（23.1%）。灾难化和抑郁是 CFS 患者慢性广泛性肌肉骨骼疼痛的即时和长期主要疼痛预测因子。它们与日常功能相关，抑郁是基线时日常功能受限的主要预测因子。
