Stögmann W
Gottfried von Preyer'sches Kinderspital der Stadt Wien.
Padiatr Padol. 1990;25(4):249-58.
Atopic dermatitis (a. D.) is a chronically relapsing inflammatory disease of the skin caused by a genetically transmitted hypersensitivity to environmental substances. Its pathogenesis is complex and multifactorial: heredity of atopic constitution, disturbances of humoral (hyperimmunoglobulinemia-E) and cellular (defect of suppressor-T-cells) immunity, abnormal vascular reactions and abnormal skin functions. A. D. shows different forms in different age groups: Eczema infantum in infancy, Eczema flexurarum in childhood and Neurodermatitis disseminata and pruriginosa while and after puberty. Typically for all forms is a pruritus and the status neurodermiticus. The healing of a. D. is spontaneously possible at any time, but not predictable for a special case.
特应性皮炎（AD）是一种由遗传传递的对环境物质过敏引起的慢性复发性皮肤炎症性疾病。其发病机制复杂且多因素：特应性体质的遗传、体液免疫（高免疫球蛋白E）和细胞免疫（抑制性T细胞缺陷）紊乱、异常血管反应和异常皮肤功能。AD在不同年龄组表现出不同形式：婴儿期的婴儿湿疹、儿童期的屈侧湿疹、青春期及青春期后泛发性神经性皮炎和痒疹。所有形式的典型表现是瘙痒和神经性皮炎状态。AD在任何时候都有可能自愈，但对于个别病例无法预测。
