Department of Organic Chemistry, Faculty of Chemistry & Technology, University of Split, N. Tesle 10/V, HR-21000 Split, Croatia.
Molecules. 2012 Feb 20;17(2):2058-72. doi: 10.3390/molecules17022058.
GC and MS were used for the analysis of Croatian Centaurium erythraea Rafn essential oil (obtained by hydrodistillation) and headspace (applying headspace solid-phase microextraction). The headspace contained numerous monoterpene hydrocarbons (the major ones were terpinene-4-ol, methone, p-cymene, γ-terpinene and limonene). Oxygenated monoterpenes were present in the headspace and oil, while 1,8-cineole, bornyl acetate and verbenone were present only in the headspace. High headspace percentages of toluene and naphthalene were found, followed by hemimellitene. Lot of similarities were observed with Serbian C. erythraea oil [neophytadiene (1.4%), thymol (2.6%), carvacrol (6.1%) and hexadecanoic acid (5.7%)], but different features were also noted such as the presence of menthol, menthone and phytone. The oil fractionation enabled identification of other minor compounds not found in total oil such as norisoprenoides, alk-1-enes or chromolaenin. The essential oil showed antimicrobial potential on Escherichia coli, Salmonella enteritidis, Staphylococcus aureus and Bacillus cereus. On the other hand, no antibacterial activity of the oil was observed on Pseudomonas fluorescens and Lysteria monocytogenes.
GC 和 MS 用于分析克罗地亚 Centaurium erythraea Rafn 精油（通过水蒸馏获得）和顶空（应用顶空固相微萃取）。顶空包含大量的单萜烃（主要的是萜品醇-4-醇、甲酮、对伞花烃、γ-萜品烯和柠檬烯）。含氧单萜存在于顶空和油中，而 1,8-桉叶素、乙酸龙脑酯和马鞭草酮仅存在于顶空。发现甲苯和萘的顶空百分比很高，其次是 hemimellitene。与塞尔维亚的 C. erythraea 油有很多相似之处[新植二烯（1.4%）、百里酚（2.6%）、香芹酚（6.1%）和十六烷酸（5.7%）]，但也注意到了不同的特征，如薄荷醇、薄荷酮和植酮的存在。油的分馏能够鉴定出总油中未发现的其他少量化合物，如 norisoprenoides、链烯或 chromolaenin。该精油对大肠杆菌、肠炎沙门氏菌、金黄色葡萄球菌和蜡状芽孢杆菌具有抗菌潜力。另一方面，油对荧光假单胞菌和单核细胞增生李斯特菌没有抗菌活性。
