Department of Vascular Surgery, Hamad General Hospital, Doha, Qatar.
Angiology. 2013 Feb;64(2):98-104. doi: 10.1177/0003319711436078. Epub 2012 Feb 19.
We evaluated the prevalence, predictors, and outcome of peripheral arterial disease (PAD) among hemodialysis (HD) patients (n = 252) in a prospective study (3-year follow-up) conducted in Qatar. Those with PAD (n = 97; 38.5%) were older and more likely to be males and to have diabetes mellitus, prior coronary artery disease (CAD), or cerebrovascular disease. Diabetic retinopathy was an independent predictor of PAD (adjusted odds ratio: 2.7; P = .004). Women had a higher mortality. Three-year all-cause mortality was high in the PAD group (adjusted hazard ratios [HRs] 2.92; 95% confidence interval [CI] 1.55-5.51). Other predictors of mortality were age (HR 1.06; 95% CI 1.04-1.10), number of vascular access (HR 2.3; 95% CI 1.04-5.01), and prior CAD (HR 1.8; 95% CI 1.05-3.49). Prevalence of PAD was high among HD patients. Early detection of PAD as well as diabetic retinopathy is of value in identifying an even higher risk population among HD patients.
我们在卡塔尔进行了一项前瞻性研究（3 年随访），评估了 252 名血液透析（HD）患者中周围动脉疾病（PAD）的患病率、预测因素和结局。97 名（38.5%）患有 PAD 的患者年龄更大，更可能是男性，且患有糖尿病、先前的冠状动脉疾病（CAD）或脑血管疾病。糖尿病视网膜病变是 PAD 的独立预测因素（调整后的优势比：2.7；P =.004）。女性的死亡率更高。PAD 组的 3 年全因死亡率较高（调整后的危险比 [HR] 2.92；95%置信区间 [CI] 1.55-5.51）。死亡率的其他预测因素包括年龄（HR 1.06；95% CI 1.04-1.10）、血管通路数量（HR 2.3；95% CI 1.04-5.01）和先前的 CAD（HR 1.8；95% CI 1.05-3.49）。HD 患者中 PAD 的患病率较高。早期发现 PAD 以及糖尿病视网膜病变对于识别 HD 患者中风险更高的人群具有重要价值。
