Ménérath J M, Coulangeon L M, Sole M, Sole P
Clinique Ophtalmologique, CHRU, Hôpital Saint-Jacques, Clermont-Ferrand.
Ophtalmologie. 1990 Mar-Apr;4(2):162-6.
Two fluorophotometric methods, by instillation and oral route, allowed the aqueous humor flow measurement and apparent outflow resistance calculation in normal and hypertensive subjects. There was no statistically significant difference between the two methods in the aqueous humor flow of hypertensive patients and normal subjects. On the contrary, there was an increase of the outflow resistance in hypertensive patients in relation to normal subjects. Finally, oral route fluorophotometry allowed the individualization and calculation of a coefficient of aqueous humor production from the iris, which is statistically increased in hypertensive in comparison with normal subjects. Subsequent studies thanks to this fluorophotometric method by oral route, which interest is certain in treated hypertensive patients, should allow to determine the action site of the drug and to quantify its efficiency.
两种荧光光度法，即滴注法和口服法，可用于测量正常人和高血压患者的房水流量并计算表观流出阻力。在高血压患者和正常受试者的房水流量方面，两种方法之间没有统计学上的显著差异。相反，与正常受试者相比，高血压患者的流出阻力增加。最后，口服荧光光度法可以个体化并计算虹膜产生房水的系数，与正常受试者相比，高血压患者的该系数在统计学上有所增加。借助这种口服荧光光度法进行的后续研究，对于接受治疗的高血压患者肯定具有重要意义，应该能够确定药物的作用部位并量化其疗效。
