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肿瘤学领域的代谢组学:近期研究综述。

Metabolomics in the fields of oncology: a review of recent research.

机构信息

Department of Surgery, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai 200072, PR China.

出版信息

Mol Biol Rep. 2012 Jul;39(7):7505-11. doi: 10.1007/s11033-012-1584-1. Epub 2012 Feb 16.

Abstract

The study of all endogenously produced metabolites, known as metabolomics, is the youngest of the "omics" sciences. It is becoming increasingly clear that, of all of the "omics" techniques, metabolomic approaches will become increasingly useful in disease diagnosis and have potential power to improve our understanding of the underlying mechanisms of cancer. The primary aim of the review is to discuss the relationship between metabolomics and tumors are elucidated in detail. Then the review is also to introduce the technologies of metabolomics, especially emphasizing the application of metabolomics in the fields of oncology.

摘要

对所有内源性代谢产物的研究,被称为代谢组学,是“组学”科学中最年轻的一个。越来越明显的是,在所有“组学”技术中,代谢组学方法在疾病诊断方面将变得越来越有用,并有可能增进我们对癌症潜在机制的理解。本综述的主要目的是详细讨论代谢组学与肿瘤之间的关系。然后,该综述还介绍了代谢组学技术,特别是强调了代谢组学在肿瘤学领域的应用。

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