Human leucocyte differentiation antigens: review of the CD nomenclature.

In February 1989 the 4th International Workshop and Conference on Human Leucocyte Differentiation Antigens was held in Vienna. At this meeting the structure and function of recognized cellular antigens was reviewed and new antigens defined. In addition, information was obtained on the molecular genetics of antigens from gene cloning and sequencing. The CD (clusters of differentiation) nomenclature was extended, giving a total of 78 CD clusters, and some previously described CD groups revised and sub-divided. In this paper new information on the structure and function of leucocyte antigens presented at the meeting will be discussed. In addition, descriptions of the newly defined CD clusters and changes to established clusters will be outlined.