Akcay Ahmet, Akar Melek, Oncel M Yekta, Kızılelma Avidan, Erdeve Omer, Oguz S Suna, Uras Nurdan, Dılmen Ugur
Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey.
Pediatr Dermatol. 2013 Jan-Feb;30(1):120-3. doi: 10.1111/j.1525-1470.2011.01716.x. Epub 2012 Feb 22.
Subcutaneous fat necrosis is an inflammatory disorder of adipose tissue. Although patients need long-term follow-up to prevent hypercalcemia, the prognosis is generally favorable. We herein present a case of a newborn who developed subcutaneous fat necrosis-related hypercalcemia after hypothermia treatment for hypoxic ischemic encephalopathy. Widespread use of hypothermia treatment for hypoxic ischemic encephalopathy in the neonatal intensive care unit may increase the risk of developing subcutaneous fat necrosis and subsequently hypercalcemia. Great care should be taken to recognize skin findings early in newborns receiving hypothermia treatment, and those diagnosed with subcutaneous fat necrosis require close follow-up because they are at risk for developing hypercalcemia.
皮下脂肪坏死是一种脂肪组织的炎症性疾病。尽管患者需要长期随访以预防高钙血症，但总体预后良好。我们在此报告一例新生儿，其在接受低温治疗缺氧缺血性脑病后发生了与皮下脂肪坏死相关的高钙血症。在新生儿重症监护病房中广泛使用低温治疗缺氧缺血性脑病可能会增加发生皮下脂肪坏死及随后高钙血症的风险。对于接受低温治疗的新生儿，应格外注意早期识别皮肤表现，而那些被诊断为皮下脂肪坏死的患儿需要密切随访，因为他们有发生高钙血症的风险。
