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澳大利亚 COPD 死亡率预测:2006-2025 年。

Forecasts of COPD mortality in Australia: 2006-2025.

机构信息

School of Public Health, La Trobe University, Rm 129, Health Sciences 1, Bundoora, Victoria 3086, Australia.

出版信息

BMC Med Res Methodol. 2012 Feb 21;12:17. doi: 10.1186/1471-2288-12-17.

Abstract

BACKGROUND

Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately over the period 2006-2025.

METHODS

Annual COPD death rates in Australia from 1922 to 2005 for age groups (50-54, 55-59, 60-64, 65-69, 70-74, 75-79, 80-84, 85+) were used. Functional time series models of age-specific COPD mortality rates for men and women were used, and forecasts of mortality rates were modelled separately for men and women.

RESULTS

Functional time series models with four basis functions were fitted to each population separately. Twenty-year forecasts were computed, and indicated an overall decline. This decline may be slower for women than for men. By age, we expect similar rates of decline in men over time. In contrast, for women, forecasts for the age group 75-79 years suggest less of a decline over time compared to younger age groups.

CONCLUSIONS

By using a new method to predict age-specific trends in COPD mortality over time, this study provides important insights into at-risk age groups for men and women separately, which has implications for policy and program development.

摘要

背景

慢性阻塞性肺疾病(COPD)是目前澳大利亚的第五大致死原因,男性和女性的死亡率趋势存在明显差异。在这项研究中,我们试图分别为男性和女性建立模型并预测 2006-2025 年期间 COPD 死亡率随时间的年龄相关变化。

方法

使用澳大利亚 1922 年至 2005 年 50-54、55-59、60-64、65-69、70-74、75-79、80-84 和 85+ 岁年龄组的 COPD 年死亡率数据。分别为男性和女性建立了特定年龄 COPD 死亡率的功能时间序列模型,并分别对男性和女性的死亡率进行了预测。

结果

为每个群体分别拟合了具有四个基函数的功能时间序列模型。计算了二十年的预测结果,表明总体呈下降趋势。女性的下降速度可能比男性慢。从年龄上看,我们预计男性的下降速度会随时间而变化。相比之下,对于女性,75-79 岁年龄组的预测表明,与年轻年龄组相比,随时间的下降幅度较小。

结论

通过使用一种新的方法来预测 COPD 死亡率随时间的特定年龄趋势,本研究为男性和女性分别提供了有关高危年龄组的重要见解,这对政策和计划的制定具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671f/3355029/8e4772799274/1471-2288-12-17-1.jpg

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