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危重症患儿的脑电图监测:适应证和策略。

Electroencephalogram monitoring in critically ill children: indications and strategies.

机构信息

Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

出版信息

Pediatr Neurol. 2012 Mar;46(3):158-61. doi: 10.1016/j.pediatrneurol.2011.12.009.

Abstract

Continuous electroencephalographic monitoring often detects nonconvulsive seizures in critically ill children, but it is resource-intense and has not been demonstrated to improve outcomes. As institutions develop clinical pathways for monitoring, they should consider how seemingly minor variations may exert substantial impacts on resource utilization and cost. In our 1-month prospective observational study, each patient in a 45-bed pediatric intensive care unit was screened for potential monitoring indications. We screened 247 patients. Minor differences in monitoring indications would exert substantial impact on resource utilization. We then calculated the number of monitoring days required each month, based on two strategies that differed in monitoring duration. The prolonged-targeted and brief-targeted strategies would have required 106 and 33 monitoring days, respectively. Based on nonconvulsive seizure occurrence data, these strategies would detect 0.14, and 0.43 patients with seizures per monitoring day performed, respectively. A brief-targeted strategy provides a high yield for nonconvulsive seizure identification, but would fail to diagnose some patients with seizures.

摘要

连续脑电图监测常用于检测危重症儿童的非惊厥性发作,但该监测方法资源密集,且尚未证明其可改善预后。随着医疗机构制定监测的临床路径,他们应考虑看似微小的差异可能会对资源利用和成本产生实质性影响。在我们为期 1 个月的前瞻性观察研究中,对 45 张病床的儿科重症监护病房中的每位患者进行了监测的潜在指征筛查。我们共筛查了 247 名患者。监测指征的细微差异将对资源利用产生实质性影响。然后,我们根据监测持续时间不同的两种策略,计算了每月所需的监测天数。延长目标监测策略和短暂目标监测策略分别需要 106 天和 33 天的监测。基于非惊厥性发作发生数据,这两种策略可分别检测到 0.14 例和 0.43 例/天的癫痫发作患者。短暂目标监测策略可提供非惊厥性发作识别的高收益,但会漏诊部分癫痫发作患者。

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本文引用的文献

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Predictors of nonconvulsive seizures among critically ill children.危重病患儿非惊厥性癫痫发作的预测因素。
Epilepsia. 2011 Nov;52(11):1973-8. doi: 10.1111/j.1528-1167.2011.03291.x. Epub 2011 Oct 17.
2
Continuous video-EEG monitoring in pediatric intensive care units.儿科重症监护病房的连续视频-脑电图监测。
Epilepsia. 2011 Jun;52(6):1130-6. doi: 10.1111/j.1528-1167.2011.03070.x. Epub 2011 Apr 19.
3
Nonconvulsive seizures are common in critically ill children.非惊厥性发作在危重症患儿中很常见。
Neurology. 2011 Mar 22;76(12):1071-7. doi: 10.1212/WNL.0b013e318211c19e. Epub 2011 Feb 9.

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