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用于修复非龋性颈病变的黏结剂:系统评价。

Adhesives for the restoration of non-carious cervical lesions: a systematic review.

机构信息

School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester M15 6FH, UK.

出版信息

J Dent. 2012 Jun;40(6):443-52. doi: 10.1016/j.jdent.2012.02.007. Epub 2012 Feb 18.

Abstract

OBJECTIVES

To establish whether simplified adhesives (self-etch) are as clinically effective as conventional adhesives (etch-and-rinse) with multiple application steps for treatment of non-carious cervical lesions (NCCLs).

NULL HYPOTHESIS

there is no difference in the clinical effectiveness of the four different bonding strategies: Three-step etch-and-rinse; Two-step etch-and-rinse; Two-step self-etch; One-step self-etch for treatment of NCCLs.

SOURCES

Electronic databases were searched including: Cochrane Oral Health Group Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE. In addition, studies were identified by handsearching of selected journals.

STUDY SELECTION

Randomised controlled trials (RCTs) comparing at least two adhesives in non-carious cervical lesions (NCCLs), with at least 18 months follow-up were selected. The primary outcome was loss of retention/restoration loss, with marginal adaptation and marginal discolouration as secondary outcomes. Criteria for quality assessment included: random sequence generation; allocation concealment; blinding of outcome assessment; and information on withdrawals. Twenty six studies were identified that met the inclusion criteria. In general, studies were not of sufficient quality to fully address the objectives of this review.

CONCLUSION

There is not enough evidence to support one adhesive or bonding strategy over another for treatment of NCCLs. Consequently, the null hypothesis of no difference cannot be supported or rejected with the data currently available. There is a need for better standardisation and reporting of randomised controlled trials investigating adhesive performance.

CLINICAL SIGNIFICANCE

Studies with low overall risk of bias demonstrated good clinical performance for adhesives with all four bonding strategies. However, included studies showed wide variation between adhesives of the same category.

摘要

目的

评估简化型黏结剂(自酸蚀)与多步骤传统黏结剂(酸蚀-冲洗)治疗非龋性颈壁缺损(NCCLs)的临床效果是否存在差异。

假设

在治疗 NCCLs 时,四种不同黏结策略(三步酸蚀-冲洗、两步酸蚀-冲洗、两步自酸蚀、一步自酸蚀)的临床效果无差异。

资料来源

电子数据库检索包括: Cochrane 口腔健康组临床试验注册库、Cochrane 对照试验中心注册库(CENTRAL)、MEDLINE 和 EMBASE。此外,还通过手检选定杂志来确定研究。

研究选择

纳入比较非龋性颈壁缺损(NCCLs)中至少两种黏结剂的随机对照试验(RCT),且随访时间至少 18 个月。主要结局为黏结保留/修复体丧失,次要结局为边缘适合性和边缘变色。质量评估标准包括:随机序列生成、分配隐藏、结局评估盲法和退出信息。符合纳入标准的研究共有 26 项。总体而言,这些研究的质量不足以完全解决本综述的目标。

结论

目前尚无足够证据支持某一种黏结剂或黏结策略优于另一种黏结剂或黏结策略用于治疗 NCCLs。因此,不能根据现有数据支持或拒绝假设无差异。需要更好地标准化和报告黏结性能的随机对照试验。

临床意义

总体偏倚风险较低的研究显示,所有四种黏结策略的黏结剂均具有良好的临床性能。然而,纳入的研究显示,同一类别黏结剂之间存在很大差异。

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