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肾脏移植的全球作用。

The global role of kidney transplantation.

机构信息

Nephrology Service, Hospital Civil de Guadalajara, University of Guadalajara Health Sciences Center Hospital, Mexico.

出版信息

Am J Nephrol. 2012;35(3):259-64. doi: 10.1159/000336371. Epub 2012 Feb 20.

DOI:10.1159/000336371
PMID:22353799
Abstract

World Kidney Day on March 8th 2012 provides a chance to reflect on the success of kidney transplantation as a therapy for end stage kidney disease that surpasses dialysis treatments both for the quality and quantity of life that it provides and for its cost effectiveness. Anything that is both cheaper and better, but is not actually the dominant therapy, must have other drawbacks that prevent replacement of all dialysis treatment by transplantation. The barriers to universal transplantation as the therapy for end stage kidney disease include the economic limitations which, in some countries place transplantation, appropriately, at a lower priority than public health fundamentals such as clean water, sanitation and vaccination. Even in high income countries the technical challenges of surgery and the consequences of immunosuppression restrict the number of suitable recipients, but the major finite restrictions on kidney transplantation rates are the shortage of donated organs and the limited medical, surgical and nursing workforces with the required expertise. These problems have solutions which involve the full range of societal, professional, governmental and political environments. World Kidney Day is a call to deliver transplantation therapy to the one million people a year who have a right to benefit.

摘要

2012 年 3 月 8 日的世界肾脏日提供了一个机会,让我们反思肾移植作为一种治疗终末期肾病的疗法所取得的成功,这种疗法在提供的生活质量和数量方面都超过了透析治疗,而且在成本效益方面也更胜一筹。任何一种既便宜又好的东西,但实际上并不是主要的治疗方法,肯定有其他的缺点,阻止了所有透析治疗都被移植所取代。将肾移植作为治疗终末期肾病的主要方法所面临的障碍包括经济限制,在一些国家,将肾移植适当地置于比清洁水、卫生和疫苗等公共卫生基本设施更低的优先级。即使在高收入国家,手术的技术挑战和免疫抑制的后果也限制了合适受者的数量,但限制肾移植率的主要限制因素是捐献器官的短缺以及缺乏具有所需专业知识的医疗、手术和护理劳动力。这些问题都有解决方案,涉及到社会、专业、政府和政治环境的各个方面。世界肾脏日呼吁为每年有权利受益的 100 万人提供移植治疗。

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J Educ Health Promot. 2021 Dec 31;10:456. doi: 10.4103/jehp.jehp_1657_20. eCollection 2021.
2
The causes and frequency of kidney allograft failure in a low-resource setting: observational data from Iraqi Kurdistan.低资源环境下肾移植失败的原因和频率:来自伊拉克库尔德斯坦的观察性数据。
BMC Nephrol. 2021 Aug 7;22(1):272. doi: 10.1186/s12882-021-02486-9.
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Stem/Stromal Cells for Treatment of Kidney Injuries With Focus on Preclinical Models.
用于治疗肾损伤的干细胞/基质细胞:聚焦临床前模型
Front Med (Lausanne). 2018 Jun 15;5:179. doi: 10.3389/fmed.2018.00179. eCollection 2018.
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J Med Biochem. 2015 Jul;34(3):295-303. doi: 10.2478/jomb-2014-0047. Epub 2015 Jul 14.
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Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients.使用免疫抑制肾移植受者血液的RNA测序技术检测差异表达的基因转录本
PLoS One. 2015 May 6;10(5):e0125045. doi: 10.1371/journal.pone.0125045. eCollection 2015.
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Kidney transplantation in a low-resource setting: Nigeria experience.资源匮乏地区的肾脏移植:尼日利亚的经验
Kidney Int Suppl (2011). 2013 May;3(2):241-245. doi: 10.1038/kisup.2013.23.