Ahmad Saqib Qayyum, Khan Obaidullah, Zafar Saerah Iffat, Zafar Saemah Nuzhat
Department of Pathology, PAF Hospital, Mianwali.
J Pak Med Assoc. 2011 Aug;61(8):817-9.
Systemic lupus erythematosus is an autoimmune disorder, which has a rare association with aplastic anaemia. A young 26 years old lady who presented with a history of intermittent fever, microcytic anaemia, joint pains and mild degree of splenomegaly was investigated. Bone marrow examination showed aplasia. Serological tests revealed positive antinuclear antibody and anti double-stranded DNA tests. Patient was diagnosed as having aplastic anaemia with Systemic lupus erythematosus, managed with steroids and being followed up for monitoring the response.
系统性红斑狼疮是一种自身免疫性疾病,与再生障碍性贫血的关联罕见。对一名26岁的年轻女性进行了检查,她有间歇性发热、小细胞贫血、关节疼痛和轻度脾肿大病史。骨髓检查显示发育不全。血清学检查显示抗核抗体和抗双链DNA检测呈阳性。患者被诊断为再生障碍性贫血合并系统性红斑狼疮,接受类固醇治疗并进行随访以监测反应。