Department of Chemistry, Zhejiang Sci-Tech University, Xiasha West Higher Education District, Hangzhou 310018, China.
J Org Chem. 2012 Mar 16;77(6):3010-6. doi: 10.1021/jo300147u. Epub 2012 Mar 5.
Functionalized allenes are efficiently synthesized in moderate to high yield from gold-catalyzed intermolecular reaction of propargylic alcohols and aromatic compounds. The user-friendly process could be conducted under mild reaction conditions with easily accessible starting materials.
金催化炔丙醇与芳基化合物的分子间反应高效合成了官能化的丙二烯,产率中等至高产。该方法使用了温和的反应条件,且原料易得,具有良好的用户友好性。