Hum Reprod. 2012 May;27(5):1231-7. doi: 10.1093/humrep/des029. Epub 2012 Feb 21.
The recent introduction of oocyte vitrification has significantly advanced the outcome of oocyte cryopreservation, leading to clinical results comparable to those achieved in IVF using fresh oocytes, as reported by experienced centres. This has lead to new debate, both in the professional community and in society at large, about the acceptability of offering this technology to reproductively healthy women who want to cryopreserve their oocytes against the threat of time. Given the many demands calling for simultaneous realization in a relatively short period of their lives, many women who want to have children feel to be under considerable pressure. The option of oocyte cryopreservation may in fact give them more breathing space. In this document, it is concluded that the arguments against allowing this application of the technology are not convincing. The recommendations include the need for adequate information of women interested in oocyte cryopreservation, also in order to avoid raising false hopes. The message must remain that women's best chances of having a healthy child are through natural reproduction at a relative early age. Centres offering this service must have the necessary expertise to employ oocyte cryopreservation efficiently with the so far non-standardized protocols. As data about long-term safety is still lacking, centres also have a responsibility to contribute to the collection of these data.
近年来，卵母细胞玻璃化冷冻技术的引入显著提高了卵母细胞冷冻保存的效果，使临床结果可与新鲜卵母细胞的体外受精相媲美，这是经验丰富的中心所报告的。这引发了新的争论，无论是在专业界还是在整个社会，都围绕着是否可以向希望冷冻保存卵子以应对时间威胁的生殖健康女性提供这项技术展开。鉴于许多需求都要求在相对较短的时间内同时实现，许多希望生育孩子的女性感到压力很大。卵母细胞冷冻保存的选择实际上可能会给她们更多的喘息空间。在本文件中，得出的结论是，反对允许将这项技术应用于这种情况的论点没有说服力。建议包括需要向有兴趣进行卵母细胞冷冻保存的女性提供足够的信息，也为了避免产生不切实际的希望。信息必须保持不变，即女性拥有健康孩子的最佳机会是通过相对较早的自然生育。提供这项服务的中心必须具备必要的专业知识，以便有效地利用目前非标准化的方案进行卵母细胞冷冻保存。由于缺乏关于长期安全性的数据，中心也有责任为这些数据的收集做出贡献。
