Kitamura S, Ishihara Y, Kosaka K, Fukushima Y
Arzneimittelforschung. 1978;28(8):1389-91.
The effect of ACTH on the actions of various bronchodilators was examined using the isolated guinea pig tracheal smooth muscle. Relaxing effects of isolated guinea pig tracheal smooth muscle with 1-isoproterenol hydrochloride, salbutamol hemisulfate, hexoprenaline hydrochloride and epinephrine except prostaglandin E2 and aminophylline were markedly potentiated by combining ACTH. These results may suggest that ACTH has a direct effect on guinea pig tracheal smooth muscle by potentiating the actions of various beta-receptor stimulators.
使用离体豚鼠气管平滑肌研究促肾上腺皮质激素（ACTH）对各种支气管扩张剂作用的影响。除前列腺素E2和氨茶碱外，ACTH与盐酸异丙肾上腺素、硫酸沙丁胺醇、盐酸海索那林和肾上腺素联合使用时，对离体豚鼠气管平滑肌的舒张作用显著增强。这些结果可能表明，ACTH通过增强各种β受体刺激剂的作用，对豚鼠气管平滑肌有直接作用。
