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[子宫内膜异位症患者生活质量评估的重要性]

[Importance of quality of life assessment in patients with endometriosis].

作者信息

Minson Fabíola Peixoto, Abrão Maurício Simões, Sardá Júnior Jamir, Kraychete Durval Campos, Podgaec Sérgio, Assis Fabrício Dias

机构信息

Programo de Dor do Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.

出版信息

Rev Bras Ginecol Obstet. 2012 Jan;34(1):11-5.

Abstract

PURPOSE

The present study examined the relationship between some clinical variables and quality of life in a group of patients with endometriosis.

METHODS

A total of 130 women seen at a multidisciplinary center specializing in gynecology endometriosis in 2008 participated in the study. This was a cross-sectional study conducted with a convenience sample. The diagnosis of endometriosis was performed by biopsy according to the criteria of the American Society for Reproductive Medicine. The clinical and demographic data were collected from the patients' records. Pain intensity was assessed by a visual numerical scale (0-10), and data on the quality of life were collected using the SF-36. Data analysis consisted of descriptive and inferential statistical tests, Spearman correlation coefficient and Kruskal-Wallis test to compare scores between groups. Nonparametric tests were used for analysis because data were not normally distributed.

RESULTS

The patients were 21 to 54 years of age or 34, standard diversion (SD)=6.56], 87% had a university degree, and 75% were married. Seventeen percent reported cases of endometriosis in the family. The average time of onset of symptoms was 4.5 years (SD=6.6), 63% of patients were in stage 3 or 4 of endometriosis 36% of patients had severe or disabling dysmenorrhea and the average intensity of pain according to a visual numerical scale was of 5.6 (SD=3.5). Results suggest that the staging of the disease did not determine the intensity of pain. The time of onset of symptoms also showed no relationship to pain intensity and SF-36 scores. On the other hand, the intensity of pain was associated with lower scores on some scales of the SF-36.

CONCLUSION

Patients with endometriosis had lower scores of quality of life than the general population and lower than those of some other diseases.

摘要

目的

本研究探讨了一组子宫内膜异位症患者的某些临床变量与生活质量之间的关系。

方法

2008年,共有130名在一家专门治疗妇科子宫内膜异位症的多学科中心就诊的女性参与了本研究。这是一项采用便利样本进行的横断面研究。根据美国生殖医学学会的标准,通过活检对子宫内膜异位症进行诊断。临床和人口统计学数据从患者记录中收集。疼痛强度通过视觉数字评分法(0 - 10)进行评估,生活质量数据使用SF - 36收集。数据分析包括描述性和推断性统计测试、Spearman相关系数以及Kruskal - Wallis检验,以比较组间得分。由于数据并非正态分布,因此使用非参数检验进行分析。

结果

患者年龄在21至54岁之间[平均年龄34岁,标准差(SD)=6.56],87%拥有大学学位,75%已婚。17%报告家族中有子宫内膜异位症病例。症状出现的平均时间为4.5年(SD = 6.6),63%的患者处于子宫内膜异位症3期或4期,36%的患者有严重或致残性痛经,根据视觉数字评分法,疼痛的平均强度为5.6(SD = 3.5)。结果表明,疾病分期并未决定疼痛强度。症状出现的时间与疼痛强度和SF - 36评分也无关联。另一方面,疼痛强度与SF - 36某些量表的较低得分相关。

结论

子宫内膜异位症患者的生活质量得分低于一般人群,且低于其他一些疾病患者。

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